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Local Anesthetic Systemic Toxicity
CA-2 · I.A.4.d.5.f II.D.10.b II.C.2.d.1.c.2
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Small patient size and sarcopenia are additional factors that increase potential risk for local anesthetic systemic toxicity (LAST).
PMID 29356773
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Using ultrasound guidance, aspiration before injection, and using the minimal local anesthetic dose needed can reduce the risk of LAST.
PMID 35777259
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LAST can present with isolated cardiovascular disturbance in one-fifth of reported cases.
PMID 30122981
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Lipid emulsion is an effective treatment for systemic toxicity induced by local anesthetics like bupivacaine.
PMID 29910676 — PMID check failed: pubmed 429 for https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&id=29910676&retmode=json&tool=intraop-teaching
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