Myocardial Injury After Noncardiac Surgery

CA-3 · II.D.1.a.3.a I.A.1.a.3

22Sources
6Kept
0Dropped

1 · Find evidence

PubMed query

Every result is a real PMID returned by NCBI. Nothing on this step is generated.

Ask OpenEvidence ↗

OpenEvidence opens in your own logged-in session with the question filled in. Nothing is fetched on your behalf — read it there, then add what you want to teach as a point below, citing the source it came from.

22 candidate papers

Ticked papers are the ones a deck may be built from. Unticking one needs a reason — the citation gate proves a paper exists, and nothing but you decides whether it should be taught. A tier badge appears where the paper’s publication type is known.

Same-day build

PubMed query

Runs the tiered searches, drafts one point per included paper, runs the citation gate and builds a draft deck — the steps below, unattended. Same-day build — drafted locally (medgemma:27b), confirmed against each abstract. The deck still lands in draft: nothing here approves anything.

2 · Teaching points

Source

A point with no source will not survive the gate. That is the point of the gate.

6 points

In patients with myocardial injury after noncardiac surgery, dabigatran 110 mg twice daily reduced major vascular complications from 15% to 11% with no significant increase in major bleeding. PMID 29900874 kept
A peak postoperative high-sensitivity troponin T of 20 to under 65 ng/L with a rise of at least 5 ng/L, or 65 ng/L and above, predicts 30-day mortality even with no ischaemic symptom or ECG change — and 93% of these patients had no symptom at all. PMID 28444280 kept
Maximum intraoperative heart rate >100 bpm is associated with increased risk of myocardial injury, myocardial infarction, and mortality after noncardiac surgery. PMID 29077608 kept
Many determinants of myocardial injury after noncardiac surgery, such as pre-existing coronary disease, cannot be changed; haemodynamic control, oxygen supply and metabolic homeostasis are the modifiable ones to act on. PMID 36931053 kept
Diagnostic thresholds are assay-specific: with the Abbott high-sensitivity troponin I assay, a peak of 60 ng/L or above carried more than a seven-fold increase in major cardiac events and death at 30 days. PMID 36682485 kept
With the ADVIA Centaur high-sensitivity troponin I assay a peak of 75 ng/L or above carried a more than five-fold increase in 30-day major cardiovascular events, and predicted them whether or not ischaemic features were present. PMID 36762424 kept

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5 · Question bank

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